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Fri 14 December, 2018 BIC  »  Team  »  Dr. N. Latha, Co-ordinator Bioinformatics Center
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lataN. Latha (Ph.D, IIT Delhi)
Associate Professor, Department of Biochemistry
& Coordinator, Bioinformatics Centre
Sri Venkateswara College, University of Delhi
Email: lata@bic-svc.ac.in

Education
  • Ph.D in the area of Bioinformatics & Computational Biology ,IIT Delhi, 2000-2004
  • M.Sc (Biochemistry) 1989-90
    University of Delhi, South Campus, New Delhi- 110021
  • B.Sc (Chemistry), 1985-1988
    Miranda House, University of Delhi-110007
Major Area of Research
Bioinformatics & Computational Biology:
Research in the area of Bioinformatics & Computational Biology under the guidance of Prof. B. Jayaram at the Department of Chemistry, Indian Institute of Technology, Delhi. The major area of research included the development of comprehensive indigenous software for active site directed drug design. This included design of a library of templates, trial structure generation fro candidate molecules, screening of these molecules for drug-like properties, Monte Carlo Docking of the candidate molecules in the active site of the drug target followed by evaluation of thermodynamic indices of binding.
  1. “In Silico Trends in Thermodynamics and Kinetics of Binding - Molecular Simulations for De Novo Drug Design”- A book review prepared & submitted for a monograph on 'Recent Trends in Chemistry' (Ed.Dr.M.M.Srivatsava) Discovery Publishers, 2001.
  2. “Active site Directed Drug Design In silico: A case study of COX-2 Inhibitors” (Abstract) Journal of Biomolecular Structure & Dynamics, June 2003.
  3. B. Jayaram, N.Latha, Tarun Jain and P. Sharma, “A comprehensive affinity based computational pathway from chemical templates to lead compounds.” Proceedings of the Indo-US workshop held from Sept 7-10, 2003 at Bangalore, India.
  4. N. Latha, Tarun Jain, Pankaj Sharma and B. Jayaram, “A Free energy based computational pathway from chemical templates to lead compounds: A case study of Cox-2 Inhibitors”, J. Biomol. Struc. Dyn. Vol 6, 2004, 791-804.
  5. Latha, N., and Jayaram, B. A Binding Affinity Based Computational Pathway for Active-Site Directed Lead Molecule Design: Some Promises and Perspectives. Drug Des. Rev.-Online. 2005, 2, 145-165.
  6. Jayaram, B., Latha, N., Jain, T., Sharma, P., Gandhimathi, A. and Pandey, V.S., Sanjeevini: A Comprehensive Active-Site Directed Lead Design Software. Ind. J. Chem. A45A, 2006, 1834-1837.
  7. Shaikh S. A., Jain T., Sandhu G., Latha N. and Jayaram B., From Drug Target to Leads- Sketching, A Physicochemical Pathway for Lead Molecule Design In Silico, Current Pharmaceutical Design, 2007, 13, 34 , 3454-3470.
  8. Shenoy, S.R., Jayaram, B. , Latha. N., et al. "From Gene to Drug: A Proof of Concept for a Plausible Computational Pathway". 6th International Conference on Intelligent Systems Design and Applications, Jinan, China, Oct. 16-18, 2006. Proceedings, IEEE Computer Society [In Press], 2006, pp. 1147-1152
Research Project
Project entitled "In silico analysis of the impact of SNPs/SNP haplotypes on protein structure and function" funded by DBT in collaboration with Prof. B. K. Thelma, Department of Genetics, University of Delhi South Campus and Prof. B. Jayaram, Head, Department of Chemistry, IIT Delhi.
 
Bioinformatics Teaching & Training
  • Coordinator of the Certificate Program in Bioinformatics & Computational Biology offered to final year science students at Sri Venkateswara College ( 2006-till date)
  • Joint Coordinator of the Certificate Programme in Bioinformatics and Computational Biology offered by Supercomputing Facility, IIT Delhi and NIIT under the aegis of FITT, IIT Delhi ( 2004-2005)
Workshops Organized
  • Convenor for the Instructional Workshop in Bioinformatics for School teachers, April 24-25, 2008  sponsored by Department of Biotechnology(DBT), Ministry of Science & Technology, Govt. of India
  • Convenor for the Bioinformatics Workshop for School Teachers held from Jan 3-5, 2008 sponsored by Department of Biotechnology( DBT),  Ministry of Science & Technology, Govt. of India
  • Coordinator for The Second ASEAN India Bioinformatics Workshop sponsored by Ministry of External Affairs and DBT , Govt. of India from Dec 14-16, 2006 at Hotel Samrat, New Delhi.
  • Convenor - organized a UGC and DBT sponsored 5-day National Workshop in Bioinformatics & Computational Biology for college teachers & research students from April 18-22, 2005 at Sri Venkateswara College, University of Delhi.
  • Co-Convener in a one-day symposium on “Emerging Trends in Bioinformatics” organized by Supercomputing Facility, IIT Delhi, NIIT and FITT, IIT Delhi on April 17, 2004 at IIT Delhi.
Lectures/ Invited Talks
  • Bioinformatics- Concepts & Applications: Miranda House, University of Delhi (Oct 2008)
  • Symposium in Bioinformatics: Department of Computer Science, University of Delhi (September, 2007)
  • Workshop in Bioinformatics: Department of Botany, University of Delhi (Feb  2007)
  • Short-Term Training Course in Computational Biology & Bioinformatics: Bioinformatics Centre, Jawaharlal Nehru university, New Delhi ( June 2005)
  • Computer Aided Drug Design:  Department of Microbiology & Biotechnology, M S University Baroda ( Feb 2005)
  • A Computational Pathway for lead molecule design: 92nd Indian Science Congress, Nirma Institute of Technology, Ahmedabad (Jan 2005)
  • Molecular Modeling: Maitreyi College, University of Delhi (September 2004)
  • Computer Aided Drug Design: NMRS Meet Kolkata, India (Feb  2004)
  • Drug Discovery & Development: Academic Staff College   Jawaharlal Nehru University, Delhi ( Jan 2003)
Poster Presentations
  • National Symposium Fourth National Symposium in Chemistry held at NCL, Pune on Feb1-3, 2002.
  • Science Day Celebrations at IIT Delhi. Presented a poster entitled “A free energy based computational pathway from chemical templates to lead molecules: A Case Study of COX-2 Inhibitors.” on the occasion of Science Day Celebrations at IIT Delhi on Feb 27-28, 2004.
  • International Conference Presented a poster entitled “Active Site Directed Drug Design: A Case Study of COX-2 Inhibitors” at the Proceedings of the 13th Conversation in the Discipline Biomolecular Stereodynamics at the State University of New York at Albany NY, U.S.A held on June17-21, 2003.

Biodtata

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